- Taurine, a typical ingredient in vitality drinks and dietary supplements, was discovered to gasoline the expansion of aggressive leukemia cells.
- Leukemia cells use a selected transporter protein to soak up taurine, and sure cells within the physique — together with these within the bones, mind, and coronary heart — are able to producing taurine naturally.
- Analysis reveals that inhibiting taurine manufacturing or its uptake by most cancers cells slowed leukemic development, indicating a possible new remedy technique.
It appears that evidently vitality drinks are all over the place. The U.S. vitality drink market alone grew by 73% between 2018 to 2023 and was valued at a staggering $23.9 billion in 2024. Nevertheless, a brand new research printed within the journal Nature offers compelling proof that, in sure circumstances, taurine, the widespread ingredient that offers these drinks their kick, could possibly be fueling extra than simply your afternoon vitality.
In Might, researchers from the College of Rochester printed their findings on taurine and its position in driving the expansion of aggressive types of leukemia.
The workforce behind the research, led by researchers on the College of Rochester, found that taurine doesn’t simply get digested if you drink it or take it in dietary supplements. As an alternative, sure cells in our bones, mind, coronary heart, and muscular tissues also can actively produce it (and it’s usually present in fish and meat as effectively). In people with leukemia, taurine seems to stimulate the multiplication of most cancers cells.
To know why, it helps to know a bit of about how blood cancers like leukemia flourish within the physique. Leukemia, the Nationwide Most cancers Institute explains, usually begins with a small variety of broken stem cells within the bone marrow, which can be the place your blood is produced. These most cancers stem cells can develop uncontrollably and hinder the physique from producing the purple and white blood cells it wants. Moreover, this new research reveals that these leukemia cells could also be nourished by the taurine your physique already produces.
The researchers found that as leukemia progresses, sure cells in human bone marrow start producing extra taurine, because the most cancers cells take in it by way of a selected protein generally known as TauT, which stands for taurine transporter. This taurine can help the most cancers cells in producing vitality extra effectively, doubtlessly inflicting them to develop at an accelerated charge.
Nevertheless, in mouse fashions, when the researchers blocked both the manufacturing of taurine within the bone or the most cancers cells’ skill to soak up it, the expansion of leukemia slowed. The mice with leukemia lived longer, and their most cancers unfold much less shortly, indicating a possible new pathway for treating this illness.
“We’re very enthusiastic about these research as a result of they show that focusing on uptake by myeloid leukemia cells could also be a doable new avenue for remedy of those aggressive illnesses,” Jeevisha Bajaj, an assistant professor within the Division of Biomedical Genetics on the College of Rochester, and lead writer of the research, shared.
It is important to know that this research doesn’t state or indicate that vitality drinks and dietary supplements will trigger most cancers in any manner. Nevertheless, it discovered that when the mice with leukemia got further taurine, much like what you’ll eat in vitality drinks, the most cancers progressed considerably quicker.
It is also vital to do not forget that taurine has been proven in early-stage research to be doubtlessly useful for folks present process chemotherapy, because it might assist mitigate unwanted side effects like nausea. Moreover, different research have additionally proven that taurine couldmight have the potential to fight gastric cancers within the abdomen.
Nonetheless, the authors concluded, “Since taurine is a typical ingredient in vitality drinks and is usually offered as a complement to mitigate the unwanted side effects of chemotherapy, our work means that it might be of curiosity to rigorously contemplate the advantages of supplemental taurine in leukemia sufferers.”